Additionally, CIDEA has shown to be down-regulated in obesity and associated with ADHD, both of which often appear in tandem with ASD (Cortese & Vincenzi, 2012; Croen et al., 2015; Kweon et al., 2018; Lee & Ousley, 2006; Nordström et al., 2005). This evidence concerns the gene CIDEA and obesity due to melanocortin 4 receptor deficiency.