CD8A and cancer: Immunohistogram describes the status of the following steps of cancer immunity cycle: step 3, priming and activation (HLA-DR); step 4, trafficking of T cells to tumors; step 5, infiltration of T cells into tumors (CD8 and TIA-1); step 6, recognition of cancer cells by T cells (HLA class I); and step 7, killing of cancer cells (PD-L1).