IL6 and steatosis: Coincident with an alleviation of hepatic steatosis, we computationally detected the downregulation of IL-6/JAK/STAT3 signaling and the inflammatory response (e.g., Tlr8, Mlkl), together with impaired EMT (Lgals1) in the liver, while the expression of genes related to mTOR was enhanced by LY (Figure 3B).