In the CASS group, PIM2, activated partial thromboplastin time, international normalized ratio, creatinine, pH value, LAC, invasive mechanical ventilation therapy, respiratory failure, renal injury, disseminated intravascular coagulation, cerebral dysfunction, and renal replacement therapy were associated with the 28-day mortality (Table 5). The gene discussed is PIM2; the disease is Disseminated intravascular coagulation.