ADARB1 and hereditary disease: The impairment of ADAR2 was implicated in several neuronal diseases in humans such as neurodegenerative disorders [21, 30, 31, 45, 56], glioblastoma [76], gastric cancer [10], the fragile X syndrome, a genetic disorder associated with cardiac diseases [21, 69], cardiovascular disease [33], and congenital heart diseases [3].