This notion is further supported by the fact that vaccination with the Oxford AstraZeneca vaccine and, more rarely, other vaccines (BBV152, “inactivated vaccine”) has also been reported before a first attack of AQP4-IgG-positive NMOSD [2, 4, 36] and other forms of CNS demyelination not associated with MOG-IgG [24, 36, 38, 44, 48]. Here, AQP4 is linked to CNS demyelination.