Previous infection with SARS-CoV-2 was explicitly reported in only one patient, who had suffered from COVID-19 nine months prior to vaccination (case 5 in the Table 1) and developed a severe attack of MOG-EM with myelitis (with swelling of the SC and paraplegia), BST and STE (diagnosed as “ADEM”) 10 days after the first dose of ChAdOx1 nCoV-19 requiring IVMP, PLEX, OS and immunosuppressive treatment with MMF. Here, MOG is linked to acute disseminated encephalomyelitis.