Claudin-low and basal-like subtypes have a place with the gathering of triple-negative breast cancer (TNBC), which are characterized by the absence of progesterone receptor (PR), ER, and HER2 articulations, and the presence of androgen receptor (AR) therefore known as LAR breast cancer subtypes with a high recurrence of visceral metastases [10]. The gene discussed is ERBB2; the disease is breast cancer.