FADS2 and metabolic syndrome: Moreover, MetS is linked to increased estimated activities of the enzymes delta-9 desaturase (D9D) and delta-6 desaturase (D6D), which catalyze the synthesis of POA from palmitic acid (PA, 16:0), oleic acid (OA, 18:1n-9) from stearic acid (SA, 18:0), and γ-linolenic acid (GLA, 18:3n-6) from LA.