Minor alleles of various FADS1 (rs174545, rs174546, rs174548, and rs174553) and FADS2 (rs1535 and rs174583) genes have been associated with an increased risk of obesity in women with a lower BMI (less than 25.0 kg·m−2) [50]. Here, FADS2 is linked to obesity due to melanocortin 4 receptor deficiency.