Patterns of serum iron markers were consistent with functional iron deficiency at early post-acute COVID-19 follow-up with a translation to absolute iron deficiency at long-term follow-up, as both serum ferritin and hepcidin concentrations were significantly higher 60 days after acute COVID-19 as compared to the one-year re-evaluation (Table 2). This evidence concerns the gene HAMP and Iron deficiency anemia.