ABO and ischemic stroke: mGWAS-Explorer revealed that the SNPs at the ABO (alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase) locus were in high LD (r2 > 0.8) with numerous other SNPs in this region associated with multiple metabolites and other human diseases, such as leucylalanine, citric acid [51], malaria [52], ischemic stroke [53], and venous thrombosis [54].