The strength of this study is that our NG and T2D women were middle-aged and from a European population, as well as being matched for BMI, WC, concentration of inflammatory markers, physical activity, alcohol consumption, smoking habits, and menopausal status, and were also free of CKD, CVD, and acute inflammation (CRP < 10 mg/L). This evidence concerns the gene CRP and type 2 diabetes mellitus.