Seven genes (PYROXD2, FADS1, PON1, CYP4F2, UGT1A8, ACADL, and LIPC) and their variants contributed significantly to trait variance for one or more metabolites.Enrichment of 6 genes was associated w/ increased ACAD activity.mQTL SNPs and mQTL-harboring genes over-represented in GWAS → implications in PCa. Here, ACADL is linked to posterior cortical atrophy.