CYP1A1 and neoplasm: The aryl hydrocarbon receptor (AhR) is a transcriptional regulator of CYP1A1, and it is reported that the AhR/CYP1A1 signaling pathway contributes to the tumor development and chemoresistance of BCSCs by inhibiting the tensin homolog and phosphatase and activating β-catenin and Akt signaling pathways [183].