Cytoskeletal genes including TTN (titin), DES (desmin), LMNA (lamin A/C), ABLIM1 (actin binding LIM domain protein), ACTN2 (α-actinin-2), NEBL (nebulette), MYPN (myopalladin), SGCD (δ sarcoglycan) and ZASP (Z band alternatively spliced PDZ domain protein) are involved in DCM [32]. This evidence concerns the gene NEBL and familial dilated cardiomyopathy.