NCAM1 and ulcerative colitis: For instance, flow cytometric analysis of peripheral blood mononuclear cells and colorectal mucosa lymphocytes in patients with ulcerative colitis and control individuals revealed that central memory T lymphocytes (CD45RA−CD62L+ T-cell subset) are increased, whereas natural killer T cells (CD56+/CD3+ subset) are decreased in the rectum of patients with ulcerative colitis [16].