CHD8 and Neurodevelopmental delay: There are over 600 confirmed human genes related to NDD (such as ID and ASD), including DNA methyltransferase 3A (DNMT3A), HECT, UBA, WWE domain-containing E3 ubiquitin-protein ligase 1 (HUWE1), and chromodomain helicase DNA-binding protein 8 (CHD8) [21,22,23].