CD274 and neoplasm: In a subgroup analysis based on the PD-L1 expression in the tumor-infiltrating immune cell (IC), the PD-L1 + group (n = 25) defined by IC2/3 (≥5%) by the SP142 Ventana assay had a higher ORR (24%) than PD-L1 IC0/1 (<5%) cohort (ORR 14%, n = 7).