TACSTD2 and metastatic malignant neoplasm in the lymph nodes: Next, our analysis of the association of Trop-2 expression with the clinicopathological profiles of 99 patients with UTUC (Table 2) indicated no association with patient sex, tumor location, tumor grade, lymphovascular invasion, or lymph node metastasis (0 vs. 1+/2+/3+; 0/1+ vs. 2+/3+; 0/1+/2+ vs. 3+).