The study shows that the levels of TC, BNP, ADMA, and mPAP in the CHD and CHD-PAH groups were considerably higher than the control group (P < 0.05), while the levels of BNP, ADMA, and mPAP in the CHD-PAH group were significantly higher than the CHD group (P < 0.01). This evidence concerns the gene NPPB and coronary artery disorder.