Scratch experiments, migration experiments and cell cycle experiments have found that TMEM88 can potently inhibit abnormal lung cancer cell proliferation, invasion and migration (26, 28), indicating that TMEM88 can exert a tumor suppressor effect and can be considered a candidate therapeutic target for the prognosis and cure of lung cancer, opening up a new avenue for the prevention of lung cancer. The gene discussed is TMEM88; the disease is lung cancer.