CEACAM5 and adenocarcinoma: Elevated CEA level (HR: 1.81, 95% CI: 1.09–3.01, p = 0.021), T4 adenocarcinoma (HR: 2.17, 95% CI: 1.26–3.75, p = 0.005), and MSI low/microsatellite stable (MSS) tumors (HR: 10.17, 95% CI: 1.41–73.18, p = 0.021) were also independent risk factors for worse RFS.