Significantly upregulated genes were CDK1, RBM3, LMNA, COL4A2, and TYMS, while the expression of KBTBD11, BCKDHB, ESR1, IYD, PDGFRA, LDLR, CA2, CCL2, ANO1, SLCO2B1, AGXT, EFHD1, and MTTP were downregulated in the tumor. The gene discussed is COL4A2; the disease is neoplasm.