MS4A4A was considered a marker of macrophages and has been associated with autoimmune conditions, such as rheumatoid arthritis (Mattiola et al., 2019), cutaneous systemic sclerosis (Rice et al., 2015), polyangiitis (Ishizu et al., 2013), and Kawasaki disease (Guo et al., 2020). This evidence concerns the gene MS4A4A and Kawasaki disease.