SMAD1 and cancer: The enrichment analysis revealed a significant association of 13 genes (ETV1, FCGR1A, HOXA10 HOXA9, MEF2C, MEIS1, PBX3, PROM1, RUNX2, SMAD1, SPINT1, SUPT3H and ZEB1) with the “Transcriptional misregulation in cancer” pathway (FDR < 0.001; Supplementary Figure S3B).