In particular, two commonly known mutations in EGFR genes, deletion of exon 19 (45–50%) and L858R point mutations in exon 21 (45%–50%), are more likely to occur in East Asians and non-smoking NSCLC patients (Shigematsu et al., 2005; Sequist et al., 2007; Ladanyi and Pao, 2008). Here, EGFR is linked to non-small cell lung carcinoma.