Cornus officinalis Siebold & Zucc. [Cornaceae] extract can promote the expression of peroxisome proliferator-activated receptor γ (PPAR-γ) in adipocytes, increase the expression of recombinant glucose transporter 4 (GLUT4) and adiponectin, improve insulin resistance, and increase glucose utilization, ultimately achieving the effect of lowering the blood sugar levels (Kim et al., 2009). This evidence concerns the gene SLC2A4 and Insulin resistance.