The result shows many interactions between the receptor HLA−DPA1 and its corresponding ligand TNFSF9 in the cell subset of macrophage and ccRCC while EGFR and MIF have strong interactions between different cell subsets (endothelia, ccRCC, vSMC) (Figure 2D). The gene discussed is EGFR; the disease is nonpapillary renal cell carcinoma.