SARS-CoV-2 D614G- and Delta- variant infection induced production of inflammatory cytokines, including high-level of IL-2, GM-CSF, KC at day 3 pi and IL-1β, TNF-α, IL-2, IL-4, IL-6, KC (Neutrophil chemoattractant) at day 7 pi. The gene discussed is TNF; the disease is infection.