Furthermore, paired sample analysis was conducted on 18 cancer types, and the results indicated that the mRNA expression of ARPC2 increased significantly in BRCA, CHOL, ESCA, HNSC, KIRC, KIRP, LIHC, and STAD tissues, whereas it was downregulated in COAD, KICH, LUAD, and PRAD (Figure 1C). This evidence concerns the gene ARPC2 and cancer.