In model 2, even further adjusting for WC, HC, WHR, WBC, NEU, ALT, AST, AST/ALT, TP, ALB, GLO, A/G, TBIL, DBIL, GGT, ALP, Urea, UA, Crea, FBG, HCY, eGFR, Height, and heart rate, the increased OR of obesity in the highest RCAN2 concentrations was also observed and higher than in model 1 (OR = 11.496, 95% CI 1.494 -88.475, p = 0.019). The gene discussed is RCAN2; the disease is obesity due to melanocortin 4 receptor deficiency.