The DBLG1 (Diabeloop, Grenoble, France) has received the CE mark in Europe for use in adults with type 1 diabetes, while the Omnipod Horizon (Insulet, Billerica, Massachusetts, USA) and insulin-only iLet (Beta Bionics, Boston, Massachusetts, USA) are currently undergoing clinical trials (49). Here, INS is linked to type 1 diabetes mellitus.