The results are in agreement with a clinical study recently published [11], where the food-grade lecithin formulation of standardized extracts of Zingiber officinale and Acmella oleracea showed a statistically significant effect on reducing symptoms of knee osteoarthritis (OA) (pain and knee function), with anti-inflammatory activity demonstrated by a reduction of specific biomarkers (C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR)). This evidence concerns the gene CRP and osteoarthritis, knee.