IQR: interquartile range; NIHSS: National Institute of Health Stroke Scale; ASPECT: Alberta Stroke Program Early Computed Tomography; TICI: Thrombolysis in Cerebral Infarction; ATA: anterior temporal artery; IA: intra-arterial thrombectomy; IV tPA: intravenous tissue plasminogen activator; LKW: last known well; CBF: cerebral blood flow (core infarct); Tmax: time to maximum (hypoperfused area). The gene discussed is PLAT; the disease is stroke disorder.