SERPINE1 and pancreatic adenocarcinoma: In this work we found that, the cluster of EMT specially enriched in MYC-TARGET_V1 pathway, and representative gene clusters such as AP3S1, BUB3, EIFD3, LDHA, NMP1, PSMD14, SERBP1, SSBP1, UBE2L3, LOX, SERPINE1, TGFBI, and CD44 that affected the overall survival of PAAD.