NR3C1 and Alzheimer disease: In addition, the levels of BDNF and activated phosphorylated TrkB (p-TrkB) were decreased in AD cases (− 33%, P = 0.001 and − 27.4%, P = 0.03, respectively) contrasting the levels of total TrkB and GR, which did not differ (Additional file 1: Fig. S3).