TNF and ataxia telangiectasia: In this study, 8 weeks of AT down-regulated gene expression of hs-CRP, IL-1β, TNF-α, IFN-γ, MAPK1, and NF-κB1 (p50), and upregulated IL-4 and PPAR-γ decreased oxidative damage (urinary 8-oHdG, glycated albumin, MDA, and hs-CRP).