CRP and coronary atherosclerosis: Use of the interaction term improved the prediction of coronary atherosclerosis beyond ACC/AHA 10-year risk score plus hs-CRP from C-statistic = 0.835 (95% CI 0.773, 0.896) to 0.862 (95% CI 0.807, 0.917), likelihood ratio test P < 0.001 (Supplemental Fig. 1).