We have found that the genetic variants in the SOD2 (c.47 T > C; rs4880), CAT (c.-89 A > T; rs7943316), GPX4 (c.660 T > A; rs713041), and NOS2 (c.1823 C > T; rs2297518) genes may modulate MS occurrence. This evidence concerns the gene SOD2 and myeloid sarcoma.