Specifically, increased Bad expression has been associated with heightened endothelial apoptosis and lung remodeling in rat models of chronic thromboembolic pulmonary hypertension (CTEPH) (Deng et al, 2017) and World Symposium on Pulmonary Hypertension (WSPH) Group 3 PH (Liu et al, 2016c). This evidence concerns the gene BAD and pulmonary arterial hypertension.