Interestingly, we found CHIT1 to significantly negatively correlate with MoCA scores in all patients (p = 1.6E-5 and r = −0.48 in all subjects; Figure S5D), and this correlation was even stronger in PD patients (p = 1.9E-9 and r = −0.81 in PD patients; Figure S5E). The gene discussed is CHIT1; the disease is Parkinson disease.