Similarly to siRNA-mediated depletion, pharmacological antagonism of DGAT1 suppressed growth of DGAT1High (A375, MM485, and SKMEL105) and DGAT1Amplified (LOXIMVI and SKMEL5) melanoma cells over 96 h (Figures 3B and S3B), accompanied by decreased cell cycle progression (Figure 3B). Here, DGAT1 is linked to melanoma.