Relative to normal tissue, HCC tumors had elevated expression of immune checkpoint markers [e.g., programmed death-ligand 1 (PD-L1), P = 2.99 × 10−2, Wilcoxon rank sum test] and activated dendritic cells (aDCs; P = 2.99 × 10−2, Wilcoxon rank sum test) (Fig. 3C and table S3A). The gene discussed is CD274; the disease is hepatocellular carcinoma.