POMC and hyperinsulinemic hypoglycemia, familial, 4: The few studies (25, 26) describing the response to ACTH 1–24 of several steroids determined by immunoassays reported also a higher progesterone, 17OHP, deoxycorticosterone and 11-deoxycortisol levels in adrenocortical incidentalomas and proposed CYP11B1 and CYP11B2 intra-tumoral deficiency.