Interestingly, CYP11B1, CYP11B2 and CYP17A1-17,20 lyase, corresponding to the most distal steps of steroidogenesis accessible by our approach on the three different pathways (glucocorticoids, mineralocorticoids and androgens, respectively), showed a decreased activity in BL patients in comparison to both control subjects and UL patients. The gene discussed is CYP11B2; the disease is Burkitt lymphoma.