In the bivariate analysis, the individual variables screened to compose the initial multiple model (p≤0.20) were: gender, age, literacy, family income, distance from the BHU, health service used, frequency of tests, frequency of access to medication, medical monitoring by the FHS, specialist monitoring, diabetes mellitus, hypertension, use of BZN in the last 2 years, functional class, NT–pro BNP, physical activity, smoking, understanding of CD, and time since the last CD visit (Table 2). This evidence concerns the gene NPPB and Hypertension.