GSEA analysis of the genesets of signatures of BRD4 (human homologues of Brd4 knockdown with p ≤ .01, unpaired t‐test and at least mean twofold decrease in expression),52 MENIN (CRISPR knockout with p ≤ .01, unpaired t‐test and at least mean twofold decrease in expression)53 and DOT1L inhibitor (EPZ004777 treatment of MOLM‐13 with p ≤ .01, unpaired t‐test and at least mean log twofold decrease in expression)17 all showed negative enrichment indicating that DSF interferes with these important signalling pathways in MLL‐rearranged leukaemias. The gene discussed is BRD4; the disease is leukemia.