IL17A and Hyperglycemia: In this work, by utilizing high-glucose (HG)-induced primary retinal Müller cells and streptozotocin (STZ)-induced wild-type (WT) and IL-17A knockout (IL-17A−/−) diabetic mice, we aimed to determine the effect of IL-17A suppression on hyperglycemia-induced Müller cell activation as well as photoreceptor cell apoptosis.