MKI67 and large cell neuroendocrine carcinoma: For tMTV (HR 1.001, p = 0.000003), tMTV dichotomised (HR 2.53, p = 0.0007), tTLG (HR 1.0001, p = 0.0000001), tTLG dichotomised (HR 2.42, p = 0.001), Ki‐67 (HR 1.02, p = 0.0003) and tumour morphology LCNEC (HR 4.25, p = 0.0008) there was very strong evidence that all were prognostic for OS including a good clinical effect size.