Although the percentage of F4/80+ CD206+ M2 cells was similar between bleomycin model of SSc and sham treated mice (60.93 ± 5.46 vs. 37.27 ± 45.37, p > 0.05, Fig. 6A), it was slightly higher in bleomycin model of SSc Capns1-ko mice. Here, MRC1 is linked to systemic sclerosis.