GSTM1 and septic shock: The RCT led by Cholette et al. (Ann Thorac Surg 2017;103:206–14) that enrolled 134 cardiac children weighing ≤ 10 kg undergoing biventricular repair cardiac surgery and the RCT led by Holst et al. (N Engl J Med 2014;371:1381–91) that enrolled 1005 adults in septic shock with an Hb concentration ≤ 9 g/dL recommended the same Hb threshold (7 g/dL).