SPRY4 and lung cancer: For instance, Hu et al., integrated lncRNAs SPRY4-IT1, ANRIL and NEAT1 in their studies on nonsmall-cell lung cancer and obtained a specificity of 92.3%, a sensitivity of 82.8%, and an AUC (ROC) (area under the ROC curve - receiver operating characteristic) of 0.87661 (Table 1).